Surprised we haven't had a "way too early" prediction thread.
Here goes nothing:
10/10/11:
Best Picture
The Artist
Descendents
Girl with the Dragon Tattoo
The Help
Moneyball
War Horse
... and for the hell of it, I'll predict Match Cut too:
Match Cut
Drive
Melancholia
Shame
Tree of Life
Uncle Boonmee Who Can Recall Past Lives